TNO plans to use food 3D printing technology for 3D printing drugs

Release date: 2016-02-29

For the field of 3D printing, the Dutch independent research institute TNO is far more than just a dark horse. In the past few years, the agency has contributed a lot of innovation in 3D printing technology, including its unique 3D printing technology. However, TNO now finds that food 3D printing technology has great similarities with 3D printing technology for pharmaceuticals.

This led TNO to decide to expand its 3D printing technology to the medical field and is experimenting with 3D printing of biocompatible oral dosage forms (ODF) for safe human intake.

The study was led by Steven Erpelinck, senior business developer at TNO's Predictive Health Technologies. TNO's R&D team is not only looking to replicate traditionally manufactured ODF through 3D printing technology, but also wants to further improve it. Through 3D printing technology, TNO believes that drugs can be developed in a more diverse and free manner. Some things can be made easier by using 3D printing technology, such as the dosage and distribution of active pharmaceutical ingredients (APIs). , the use and distribution of excipients, and the structure and shape of the tablets. Here's a complete list of potential advantages of producing Odf using 3D printing technology using 3D printing technology:

Conveniently produce different doses of ODF;

Produce a specific ODF based on a specially designed configuration file;

Easily produce ODFs containing multiple APIs;

Manufacture of ODF with specially designed internal structures (such as microchannels);

Manufacture of ODF with special shape (for marketing, anti-counterfeiting)

TNO's research and development direction is not limited to the manufacture of these ODFs, because these ODFs obviously have to pass the in vitro platform test to ensure safe consumption. To this end, they have also developed a test platform like InTESTine that replicates the functions of different parts of the human digestive system. By placing these ODFs on InTESTine, TNO was able to study how much biocompatibility these 3D printed ODFs have with the human body.

From food to pharmaceuticals, TNO continues its state-of-the-art R&D in 3D printing technology, and in the future they will continue to research their bioavailability and personalized medicine through 3D printing ODF.

Source: cnbeta website (Taizhou)

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