A new study in Japan reveals the cause of autoimmune pancreatitis, and related results can help diagnose this easily misdiagnosed disease. Autoimmune pancreatitis is a chronic pancreatitis that is difficult to diagnose and is easily misdiagnosed as pancreatic cancer. The disease is caused by the body's immune response to its own antigen, but its antigen has been unknown. Researchers at Kyoto University in Japan recently reported in the journal Science and Translational Medicine that they found that the antigen of autoimmune pancreatitis may be mainly a protein called laminin 511-E8. The researchers said that half of the patients they studied had antibodies to the protein in their bodies, which were rarely detected in healthy people. After injecting this protein into mice, the mice developed symptoms similar to autoimmune pancreatitis. The researchers say the findings help the medical community deepen its understanding of autoimmune pancreatitis and develop better methods of diagnosis and treatment.
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New research reveals the cause of autoimmune pancreatitis