Release date: 2014-06-03 Many hypertensive patients do not respond to drugs, which puts them at risk for stroke, heart failure and kidney failure. Implantable devices can lower blood pressure by stimulating the neck nerves and may replace drugs that control blood pressure in the future. This device is one of the latest research results of the recent use of nerve stimulation implants. Such devices may bring new hope to extremely severe hypertensive patients. As many as 30% of hypertensive patients cannot be completely treated with drugs, and some patients experience side effects such as fatigue and mild dizziness when taking the drug. “Implantable devices can lower the blood pressure of these patients and can be used alone or in combination with existing treatments,†says Dennis Plachta, a microsystems engineer at the University of Freiburg, Germany. Provides a new option that is not yet fully developed and can be treated with drugs." Prakhta and his team worked together to develop a micromechanical device wrapped around the vagus nerve. The vagus nerve is located in the neck and is responsible for exchanging key physiological information between the brain and other major organs, including the heart. A 20 mm long device places a set of electrodes into one area of ​​the nerve. The research team believes that this area can stimulate blood pressure changes. The researchers tested their implants on five adult mice and found that specific stimulation patterns reduced blood pressure in mice by 40% without significant side effects. Prahta said that the process of implanting the device into the human body is similar to the prior art of using vagus nerve stimulation to treat epilepsy. The first step is to cut a small incision in the left side of the neck, and then the surgeon will carefully wrap the electrode around the nerve. This device will then be connected to a capsule containing a pulse generator that will be implanted under the chest muscles through an incision in the left axilla. Prakhta said the entire operation took an hour and a half or less. According to John Bisognano, the president of the American Society of Hypertension, the results of this research are impressive, with the latest advances in microelectronics and microsurgery, and the future is promising. Bissonano is a cardiovascular doctor who runs an antihypertensive clinic at the University of Rochester Medical Center in New York. He said that patients need more treatment options, but they only take those high-pressure drugs, and some people face serious side effects, it is difficult to maintain drug treatment. "The worst thing is that blood pressure is still high, which means they face a high risk of stroke, heart failure and kidney failure," he said. The implantation of electronic device technology with controllable bodily functions has been used for many years. The pacemaker for heart disease patients is probably the most famous. Electronic devices have also been used to control Parkinson's disease and have also been used experimentally to adjust some mental states. They even help with seemingly unlikely diseases such as bladder dysfunction and rheumatoid arthritis. Kristoffer Famm, vice president of bioelectronics research and development at GlaxoSmithKline, co-authored a paper last year to explore the emerging field he and his academic colleagues call "electrotherapy." The company has invested $50 million in companies that invest in developing such technologies. Bissonano said that nerve stimulation is a logical mechanism for controlling blood pressure. It is well known that the nervous system can regulate the degree of tension in the human arteries and control the intensity and frequency of cardiac contractions. However, with the latest technology, this knowledge can be used to develop device-based therapies. Using experimental implants that directly stimulate the carotid artery, Bissonano has successfully reduced blood pressure, and the design of the device is completely different from the implant developed by the German team. Under the new design, the blood pressure of the rat decreased within 5 seconds after the device stimulated the nerve. Prahta said he and his colleagues are developing a "smart" version of the system that monitors blood pressure in real time and responds to physical needs. He said that drugs can't adapt to the patient's activities, but smart implants can provide a "custom" approach to treating high blood pressure. Source: MIT Technology Review Pickled Cucumber India,Pickled Cucumber International Paking,Pickled Gherkins 1500Ml,Pickled Cucumbers In Glass Jar Laiwu Manhing Vegetables Fruits Corporation , https://www.manhingfood.com
Implantation of nerve-stimulated electronic devices can inhibit high blood pressure