[treatment measures] 1. Young patients with benign ovarian tumors undergo ipsilateral appendectomy or tumor ablation. If both sides of the ovary have tumors, they should strive to retain some of the normal ovarian tissue. Specimens should be dissected before closing the abdomen, and suspected malignant changes should be sent to the frozen section for examination. Before and after menopause, patients should undergo full uterus and bilateral adnexectomy to prevent future problems. 2. Malignant ovarian tumors are mainly treated by surgery, supplemented by chemotherapy and radiation therapy. (1) Surgical treatment is generally performed with whole uterus, bilateral appendages, and omentum resection. In advanced patients, metastatic tumors should be removed as much as possible. As for the therapeutic value of removing retroperitoneal lymph nodes, it is still unclear. (2) Chemotherapy is the main adjuvant therapy. It is estimated that surgical resection of the tumor is difficult, and 1 to 2 courses of chemotherapy are used before surgery to improve the surgical resection. Postoperative chemotherapy can prevent recurrence; surgical resection is not complete, after chemotherapy can be temporarily relieved or even long-term survival; surgery can not be removed, chemotherapy can shrink the tumor, loose, create conditions for reoperation. The choice, dosage, use, and course of treatment for chemotherapeutic drugs have not been unified so far. From the efficacy analysis, it is better to use small doses of intermittent medications for continuous drug use. Combination chemotherapy is better than single chemotherapy. It is better to formulate chemotherapy plans according to histological classification: 1 Systemic chemotherapy is mainly based on intravenous medication. Current treatment of epithelial ovarian cancer, the use of cisplatin (DDP) and adriamycin (ADM), hexamethylene (HMM), cyclophosphamide (CTX), 5-fluorouracil (5-Fu) and other combination chemotherapy . The single dose is generally cisplatin 30 mg/m2, doxorubicin 30 mg/m2, hexamethylene melamine 150 mg/m2, (oral), cyclophosphamide 150 mg/m2, 5-fluorouracil 8 mg/kg. Ovarian germ cell tumors, commonly used VAC program, vincristine (VCR) 2mg, intravenous injection, a total of 12 times a week; Actinomycin D (KSM) 400μg, 2nd to 6th days intravenous infusion; cyclophosphamide (CTX) 400mg, intravenous injection on the 2nd to 6th days. In recent years, the use of VAC program at the same time plus DDP20mg/m m2, the first 1 to 5 days of intravenous infusion, repeat 3 to 4 weeks. Stromal stromal tumors mostly use AFC regimen, that is actinomycin D 0.01/kg, once daily intravenous infusion, a total of 5 times (maximum 0.5mg/d); 5-fluorouracil 8mg/kg, each Daily intravenous infusion, a total of 5 times; cyclophosphamide 7mg/kg, intravenous injection once a day, a total of 5 times. Repeat every 4 weeks. 2 Intraperitoneal chemotherapy can directly act on the tumor, local concentration is high, the detection of ascites is effective, and the side effects are lighter. At present, cisplatin 60 ~ 80mg plus normal saline 1000ml, while the line of hydration, 24-hour urine output of 2000ml or more to reduce the nephrotoxicity. 3 arterial injection chemotherapy in local anesthesia, percutaneous femoral artery, retrograde intubation into the internal iliac artery injection of anti-cancer drugs, can reduce the combination of anti-cancer drugs and plasma protein, and increase the free drug concentration; can increase anti-cancer The cytotoxic effect of the drug improves the efficacy. In addition, systemic side effects can still be reduced. 4 Chemoembolization simultaneously instills anticancer drugs and embolic agents into the arteries, so that cancer cells that are affected by anticancer drugs undergo hypoxia-ischemia and are more likely to become necrotic. (3) Fear in the treatment of ovarian malignancies of different tissue types, the sensitivity to radiotherapy is different, asexual cell tumors are most sensitive to radiotherapy, granular cell tumors are moderately sensitive, and epithelial tumors also have a certain sensitivity; postoperative external irradiation is mainly For the abdominal cavity residual cancer. Intra-abdominal non-adhesive small residual cancer can be injected 7 to 14 days after surgery radionuclide, commonly used 32P10 ~ 15mCi, set 300 ~ 500ml of normal saline, slowly injected into the abdominal cavity. 4, anti-cancer Chinese medicine treatment can be used as one of the comprehensive treatment measures, apply to some patients who are not suitable for surgery and radiotherapy, chemotherapy or recurrence after surgery. The Fushan Chinese Medicine Cancer Hospital of Hebei Province used high-tech achievements to develop cell molecule modulators to suppress cancer "Chinese Fusanshen" series preparations (water pills, capsules, oral liquids, etc.) and anticancer injections, breaking the "cancer, cancer, and anti-cancer "The traditional thinking of cancer" is that the drug itself is not toxic and it does not directly stimulate the cancer. It is a clinical application of cell gene therapy. The principle of its cancer is: to inhibit the formation of cancerous neovascular network, block the nutritional supply of cancer cells, cut off the metabolic channels of cancer cells, resulting in cancer tumors can not get nutrients and gradually withered, waste can not be excreted and gradually degenerate, And it does not harm normal cells. In enhancing the body's own immune function, promoting the regeneration of the body's anti-cancer immune monitoring system, activating various types of cancer cells while regulating the cell cycle engine molecules and cell motility, so that uncontrolled cancer cells return to normal cycle rhythm, let cancer cells A reversal occurred. The drug combined with radiotherapy and chemotherapy can significantly reduce the toxic and side effects of radiotherapy and chemotherapy, and increase the number of white blood cells. Even advanced patients who have lost surgery or chemoradiation can control metastasis, reduce cancer pain, improve symptoms, improve quality of life, and prolong cancer-free survival. Medical Boiling Machine,Hospital Supply Room Boiling Machine,Medical Device Boiling Machine,Hospital Boiling Machine Taizhou Gaogang District Dixin Medical Equipment Co., Ltd. , https://www.dixinmedical.com
Comprehensive treatment of ovarian tumors
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