Anti-Inflammatory Drug Mometasone Furoate CAS: 83919-23-7

Anti-Inflammatory Drug Mometasone Furoate CAS: 83919-23-7

Model NO.: 83919-23-7
Mf: C32h32cl2o8
MW: 615.5
Trademark: JCJ
Transport Package: 1kg Foil Bag
Specification: USP
Origin: China
HS Code: 1111111111
Model NO.: 83919-23-7
Mf: C32h32cl2o8
MW: 615.5
Trademark: JCJ
Transport Package: 1kg Foil Bag
Specification: USP
Origin: China
HS Code: 1111111111
Anti-inflammatory Drug Mometasone Furoate CAS: 83919-23-7

Description:

Mometasone Furoate is the furoate salt form of mometasone, a synthetic topical glucocorticosteroid receptor agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Mometasone furoate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.. Specifically, mometasone furoate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2.

Basic information:

Chemical name: MOMETASONE FUROATE
MF: C32H32Cl2O8
MW: 615.5
CAS: 83919-23-7
Purity: over 99%
Appearance: white powder
Package: 1KG foil bag
Usage:  anti-inflammatory agent

COA:

 
Product name Mometasone Furoate
CAS No. 83919-23-7 Outer Packing 1KG
Production date 2017.11.15 Shelf life 2019.11.14
Standard adopted USP38
Items of analysis Specification Results
Description White to off-white powder
Conform
Identification A:IR B:HPLC Conform
Melt Point About 220ºC 220.5ºC
Specific Rotation +56 -+62 ° +58.4°
Loss on drying ≤0.5% 0.31%
Residue On Ignition ≤ 0.1% 0.08%
Heavy Metals ≤30 ppm Conform
Single impurity ≤1.0% Conform
Sum impurity ≤2.0% Conform
Assay 97-102% 99.36%
Particle size Micronized Conform
Conclusion Qualified

Medical uses:

Mometasone furoate is used in the treatment of inflammatory skin disorders (such as eczema and psoriasis) (topical form), allergic rhinitis (such as hay fever) (topical form), asthma (inhalation form)for patients unresponsive to less potent corticosteroids, and penile phimosis.In terms of steroid strength, it is more potent than hydrocortisone, and less potent than dexamethasone.

Some low-quality evidence suggests the use of mometasone for symptomatic improvement in children with adenoid hypertrophy.

Mometasone is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis.[8][9]

Nasal mometasone is used in adults (including the elderly) and children over two years of age, to diminish the symptoms such as hay fever (seasonal allergic rhinitis) and other allergies (perennial rhinitis), including nasal congestion, discharge, pruritus, and sneezing and to treat nasal polyps.

How to use Mometasone FUROATE Ointment?

Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is for use only on certain areas of skin: do not use it on the face, groin, or underarms, or for diaper rash, unless directed to do so by your doctor.

Wash and dry your hands before using. Clean and dry the affected area. Apply as directed by your doctor, usually a thin film of medication to the affected area once daily. Gently rub in. Do not cover the treated area with bandages or other dressings unless instructed to do so by your doctor. If used near the diaper area on an infant, do not use tight-fitting diapers or plastic pants.

Do not wash or rinse the medication off immediately after applying it. Wash your hands with soap and water after each use unless you are using this medication to treat the hands. Avoid getting this medication in your eyes, nose, or mouth. If this occurs, rinse thoroughly with water and call your doctor if irritation persists.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day. Do not apply large amounts of this medication, use it more often, or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects may increase.

Our Advantages:

1. Good reputation:
Our company is a leading chemical company in China, and has more than 16 years history. We have over 10 branch offices, all enjoy good reputation from worldwide customers.

2. High Quality&low price
All of our products have top quality and high purity, since we are the factory, our price is competitive.

3. Multiple payment methods.
We have mutiple payment methods, T/T, Western Unoin, MoneyGram, and Bitcoin for your convenience.

4. Mass Stock
In order to better serve our customers, we are preparing mass stock in our warehouse, we can always ship your parcel within 24 hours.

5. High customs clearance pass rate.
Through 16 years hard work, we have accumulated rich exporting experience to USA, UK, France, Italy, Germany,Spain, Brail, korea, India and so on.We will use special ways to disguise the goods, 98% customs clearance rate is guaranteed, if the delivery is not successful, we will resend for free.

6. Warm After service.
If you have any problems about the goods, do no hesitate to contact us, we can provide 7/24 service.

How to proceed an order:

Step 1:when you intended to buy something, pls send me an inquiry by email, skype or whatsapp.
Step2:I will reply you with a quotation as soon as I receive you inquiry.
Step3:we will negotiate products, price, package, payment methods and so on.
Step4:you arrange the payment.
Step5:i will arrange the shipment after receiving you money.
Step6:the tracking number and the picture of the parcel will be sent to you.
Step7:trace the tracking number on website until you receive the goods.
Step8:if you have any questions about the goods, pls contact me, i will try my best to satisfy you.

If you have any questions, please feel free to contact me:

Tel: +8618872220738

  Anti-inflammatory Drug Mometasone Furoate CAS: 83919-23-7

Description:

Mometasone Furoate is the furoate salt form of mometasone, a synthetic topical glucocorticosteroid receptor agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Mometasone furoate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.. Specifically, mometasone furoate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2.

Basic information:

Chemical name: MOMETASONE FUROATE
MF: C32H32Cl2O8
MW: 615.5
CAS: 83919-23-7
Purity: over 99%
Appearance: white powder
Package: 1KG foil bag
Usage:  anti-inflammatory agent

COA:

 
Product name Mometasone Furoate
CAS No. 83919-23-7 Outer Packing 1KG
Production date 2017.11.15 Shelf life 2019.11.14
Standard adopted USP38
Items of analysis Specification Results
Description White to off-white powder
Conform
Identification A:IR B:HPLC Conform
Melt Point About 220ºC 220.5ºC
Specific Rotation +56 -+62 ° +58.4°
Loss on drying ≤0.5% 0.31%
Residue On Ignition ≤ 0.1% 0.08%
Heavy Metals ≤30 ppm Conform
Single impurity ≤1.0% Conform
Sum impurity ≤2.0% Conform
Assay 97-102% 99.36%
Particle size Micronized Conform
Conclusion Qualified

Medical uses:

Mometasone furoate is used in the treatment of inflammatory skin disorders (such as eczema and psoriasis) (topical form), allergic rhinitis (such as hay fever) (topical form), asthma (inhalation form)for patients unresponsive to less potent corticosteroids, and penile phimosis.In terms of steroid strength, it is more potent than hydrocortisone, and less potent than dexamethasone.

Some low-quality evidence suggests the use of mometasone for symptomatic improvement in children with adenoid hypertrophy.

Mometasone is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis.[8][9]

Nasal mometasone is used in adults (including the elderly) and children over two years of age, to diminish the symptoms such as hay fever (seasonal allergic rhinitis) and other allergies (perennial rhinitis), including nasal congestion, discharge, pruritus, and sneezing and to treat nasal polyps.

How to use Mometasone FUROATE Ointment?

Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is for use only on certain areas of skin: do not use it on the face, groin, or underarms, or for diaper rash, unless directed to do so by your doctor.

Wash and dry your hands before using. Clean and dry the affected area. Apply as directed by your doctor, usually a thin film of medication to the affected area once daily. Gently rub in. Do not cover the treated area with bandages or other dressings unless instructed to do so by your doctor. If used near the diaper area on an infant, do not use tight-fitting diapers or plastic pants.

Do not wash or rinse the medication off immediately after applying it. Wash your hands with soap and water after each use unless you are using this medication to treat the hands. Avoid getting this medication in your eyes, nose, or mouth. If this occurs, rinse thoroughly with water and call your doctor if irritation persists.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day. Do not apply large amounts of this medication, use it more often, or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects may increase.

Our Advantages:

1. Good reputation:
Our company is a leading chemical company in China, and has more than 16 years history. We have over 10 branch offices, all enjoy good reputation from worldwide customers.

2. High Quality&low price
All of our products have top quality and high purity, since we are the factory, our price is competitive.

3. Multiple payment methods.
We have mutiple payment methods, T/T, Western Unoin, MoneyGram, and Bitcoin for your convenience.

4. Mass Stock
In order to better serve our customers, we are preparing mass stock in our warehouse, we can always ship your parcel within 24 hours.

5. High customs clearance pass rate.
Through 16 years hard work, we have accumulated rich exporting experience to USA, UK, France, Italy, Germany,Spain, Brail, korea, India and so on.We will use special ways to disguise the goods, 98% customs clearance rate is guaranteed, if the delivery is not successful, we will resend for free.

6. Warm After service.
If you have any problems about the goods, do no hesitate to contact us, we can provide 7/24 service.

How to proceed an order:

Step 1:when you intended to buy something, pls send me an inquiry by email, skype or whatsapp.
Step2:I will reply you with a quotation as soon as I receive you inquiry.
Step3:we will negotiate products, price, package, payment methods and so on.
Step4:you arrange the payment.
Step5:i will arrange the shipment after receiving you money.
Step6:the tracking number and the picture of the parcel will be sent to you.
Step7:trace the tracking number on website until you receive the goods.
Step8:if you have any questions about the goods, pls contact me, i will try my best to satisfy you.

If you have any questions, please feel free to contact me:

Tel: +8618872220738

 

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