Gene editing research is one of the top ten scientific events in Nature in 2015, and CRISPR is a revolutionary gene editing technology that will potentially eliminate diseases and bring about a huge change in biomedical research. . Dr. Lei Lei, a Chinese scientist at Stanford University, has made a series of breakthroughs in the field of CRISPR research in recent years. He said: "We are considering how to use our tools to implement new treatments for in vivo gene therapy or cancer immunotherapy." On the occasion of the WE conference, Tencent's chief exploration official website was a dialogue with Dr. Lei Lei to discuss the hottest topics in life sciences. What is the Nobel Prize popular CRISPR? If the discovery of DNA allows humans to open the book of life passwords, then the emergence of gene editing technology shows that human beings are not satisfied with the simple interpretation of the book, but begin to rewrite the trajectory of life. Netizen said that many people don't understand how genetic editing is all about it. How does the application of Yan Lei benefit people? Dr. Lei Lei said that if the password of life is explained in one sentence, it is "DNA makes RNA, RNA makes protein, protein forms human body", which is also called "central rule". It is very important that genetic information flows according to this law. Once there is a problem with this process, genetic defects will occur, leading to mutations in the disease. “Everything starts with DNA. After understanding, we begin to understand whether our genetic engineers can design, test, make it better, fix problems, and prevent problems.†Yu Lei further explained that it is necessary to use CRISPR, which is the abbreviation of “Clustered Regularly Interspersed Short Palindromic Repeatsâ€, which is not the longest in biology, but It must be the hottest in the near future. The reason for having such a long name is because it was not created by any biologist or scholar, but from bacteria. Bacteria use this system to create a simple but highly efficient immune system. Yan Lei said that bacteria can also be infected by viruses. When bacteria invade a virus, it will recognize it with its own RNA. Once the virus species is identified, it will induce the expression of the CRISPR sequence, which will cut off the corresponding DNA DNA. Sequence, thus killing the virus and protecting yourself.
Ulcers is commonly known as gastric ulcer and duodenal ulcer, the formation of ulcers is closely related with gastric acid or pepsin digestion. Ulcer disease is a chronic disease, its seizures were cyclical, episodes and remission of alternating appear, and the onset of abdominal pain has a certain rule. The main cause of ulcers include: 1. Helicobacter pylori infection 2. Bad diet 3. Mental factors 4. Drug stimulation. Many patients with gastric ulcer who have taken non-steroidal anti-inflammatory drug history, these drugs will stimulate our gastric mucosa, causing damage, then it will cause ulcer disease over time. The current anti-ulcer drug is mainly focused on reducing gastric acid and enhance the protective effect of gastric mucosa. In recent years,the research and development of anti-ulcer drug progress is faster, effective drugs have been listed, sales are also rising.
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Tencent also wants to enter the genetic editing of the master: How does the genetic switch benefit humanity?