Save lives! Is the chip so amazing?

A tiny biomedical device was born, according to its developers, this device can minimize the invasion and detect cancer at an early stage. The on-chip laboratory works by detecting a tiny cell vesicle-secreting fluid that can be used to find most tumor cells.

At present, this cyst fluid is difficult to separate and detect because it is very small (about 30-150 nm).

However, a team from the University of Kansas invented an instrument that guarantees a short diagnosis time and reduces costs. It is needed for small sample detection and high sensitivity analysis compared to traditional benchtop instruments, and it can be quickly used to detect tiny organisms.

The on-chip lab was originally called polydimethylsiloxane, which is widely used with silicone rubber and a technique called on-chip immunoisolation.

“We used a magnetic bead with a diameter of 3 μm to reduce the liquid sample of the plasma,” explains Zeng Yong, an assistant professor at the University of Kansas. “In order to prevent other interfering substances from being present in the plasma, the surface of the bead is recognized and bound to a specific target protein. The antibody undergoes chemical changes, for example, protein receptors - appearing on foreign body membranes."

The plasma contains magnetic beads, so the microplasma reaches the chip through the microchannel, and the magnetic beads can be collected by magnetism, which in turn can circulate in the plasma.

This device is currently used to detect lung cancer, although Mr. Zeng explained that it can potentially detect different forms of disease.

“We have provided a universal detection platform that can detect cancer by detecting cystic fluid,” he continued. “In addition to lung cancer, we can also detect ovarian cancer. In theory, it can also detect other types of cancer.”

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