Release date: 2015-12-25 Recently, Wu Chengtie, a researcher at the Shanghai Institute of Ceramics of the Chinese Academy of Sciences, and a research team led by Chang Jiang first proposed the idea of ​​combining bone tissue engineering with photothermal therapy to prepare photothermal functionalization for the treatment and repair of bone tumor defects. New progress has been made in the study of bioactive ceramic scaffolds. In this study, the bioceramic and graphene oxide composite scaffolds were prepared by 3D printing technology, and the temperature of the scaffold was rapidly increased under ultra-low power near-infrared light, and its photothermal performance was controllable. Implantation of the functionalized scaffold in mice and light irradiation effectively inhibited the growth of subcutaneous tumors in nude mice, while the tumor volume of the control group continued to increase with the number of days. At the same time, the scaffold can significantly promote the proliferation and osteogenic differentiation of bone mesenchymal stem cells, and induce the growth of new bone tissue in vivo, thus conferring bifunctionality on the anti-tumor and bone repair of 3D printed bioceramic scaffolds. There are potential applications in the treatment and repair of tumors. At present, the research results are received Advanced Functional Materials (first author of the paper as a doctoral candidate Ma Redstone). The reviewer spoke highly of the study: “This is a well-designed study with significant innovation that solves the problem that traditional bioscaffolds cannot combine both tumor therapy and bone repair.†Currently, the results have been applied. A patent. In addition, through three years of exploration, the research team successfully solved the problem that the large-scale and large-hole structure controllability of the traditional 3D printed bioceramic stent is not high. Recently, the team also successfully produced bioceramic scaffolds with multi-scale and complex structures using 3D printing methods, including bioceramic hollow tubular stacked porous scaffolds and porous mesoporous composite scaffolds. These new scaffold materials are more The complex structure of human tissue is well simulated, and its osteogenesis and vascularization performance are significantly improved. Source: Medical Machinery Innovation Network We are a professional Chinese manufacturer of Female Health Care Material;we supply various products of Woman's Health Materials, and can providing product images and basic parameters with each Woman's Health Materials and Breast Enlarghe Material. We have the perfect after-sales service and technical support. Please do not hesitate to contact us, Look forward to your cooperation! Woman's Health Materials,Soy Isoflavones,Radix Puerariae Extract,Flax Seed Extract,Breast Enlarghe Material Xi'an Quanao Biotech Co., Ltd. , https://www.quanaobiotech.com
Chinese Academy of Sciences scientists 3D printed bioceramic stent can be used for bone tumor treatment